When I worked at Expedia as a contractor, I was placed on the EPC (Expedia Partner Central) design team to help redesign their responsive website for hoteliers. All designs at the time were done using Adobe Illustrator. I lead a new initiative to use their existing dev team component library and online style guide to create high fidelity mockups and fully functional prototypes. By the time I left the company, they had incorporated a whole new prototyping system inspired by my prototyping work.
Below are some examples of fully responsive pages and templates I created for my high fidelity mockups and advanced prototypes.